The Kidney Foundation of Canada will be celebrating its 60th anniversary at an Evening of Hope on Wednesday, June 5, 2024, at the York Mills Gallery. Emceed by investigative reporter and kidney transplant recipient, Cristina Howorun, An Evening of Hope will celebrate the deep commitment of thousands...
Nights are getting shorter; the leaves are changing colour - fall is in the air. It’s also the time of year when colds, flus and other illnesses are on the rise. People living with kidney disease are at higher risk from severe illness from the flu, RSV and COVID-19, and may be more susceptible to...
2023 - 2025
$120,000
Transplantation, Chronic Kidney Disease, Acute Kidney Injury
Hepatocyte Nuclear Factor 4 Alpha (HNF4A) as a Regulator of Kidney Graft Repair
Lay Abstract
Kidney transplantation is the ideal treatment for patients whose kidneys fail. Unfortunately, there are not enough kidneys...
2023 - 2025
$120,000
Kidney Biology, Chronic Kidney Disease
Altered mitochondrial dynamics and the underlying molecular mechanisms in Polycystic Kidney Disease
Lay Abstract
How do the power plants of the cells break up in polycystic kidney disease?
Background: Chronic kidney disease (CKD),...
2025 - 2027
$120,000
Kidney Biology, Chronic Kidney Disease
Critical molecular switches in renal fibrogenesis
Lay Abstract
Background: Chronic kidney disease (CKD) is characterized by the gradual loss of kidney function. This is a common and devastating condition, affecting 12% of Canadians....
2024 - 2026
$120,000
Chronic Kidney Disease, Kidney Biology, Renal Failure
Repurposing istradefylline for kidney fibrosis
Co-Applicant(s): Darren Yuen
Lay Abstract
Despite recent advances in care, kidney failure remains a major health problem. We urgently need new treatments to prevent the...
2022 - 2024
$100,000
Glomerulonephritis, Kidney Biology
Protein kinase SLK in the kidney
Lay Abstract
The health of an organism largely depends on the accuracy of signals sent among constituent cells. Much of this information is transmitted inside cells through specific proteins, called protein...
2025 - 2027
$120,000
Glomerulonephritis
ER stress in glomerular disease: defining mechanisms and identification of new diagnostic and therapeutic targets
Co-Applicant(s): Ahsan Alam, Constantinos DELTAS, Joseph Bonventre, Louis-Philippe Laurin, Stéphane Laporte
Lay Abstract
Glomerular podocytes...
2024 - 2027
$210,000
Chronic Kidney Disease
KidneyCare Outreach: Strengthening care delivery for patients at high risk
Lay Abstract
Background: Kidney disease affects 1 in 10 Canadians. Since it often starts slowly and develops over many years without any symptoms, the disease may not be detected...