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2023 - 2026 Chronic Kidney Disease Novel therapeutic strategies in cardiorenal medicine KRESCENT Curriculum only Lay Abstract Patients with kidney disease experience frequent complications from their heart or develop clots in their blood vessels. These complications are associated with significant...

2024 - 2026 $120,000 Chronic Kidney Disease Exploiting genetic models of the proximal tubule tight junction to dissect the role of hyperphosphatemia in cardiovascular disease Lay Abstract Lay Abstract Title: Is it phosphate, FGF23 or kidney disease itself that causes heart disease in people with...

2024 - 2027 $12,000 Risk and trend in the burden of stroke among patients on chronic maintenance dialysis Supervisor(s): Aminu Bello Lay Summary Background: Patients with kidney failure undergoing chronic maintenance dialysis have a higher risk of cardiovascular diseases compared to the general...

2023 - 2025 $120,000 Transplantation, Predictive Biomarkers Multiomic characterization of chronic, active T cell-mediated rejection in pediatric kidney transplant recipients Lay Abstract For children with end-stage kidney failure, a kidney transplant is life-saving. Although there has been...

While Tom has been a dedicated volunteer and donor for many years, he wanted to ensure The Foundation’s mission continues beyond his lifetime. The Kidney Foundation of Canada deeply appreciates the generosity and unwavering support of its donors. One notable donor, Tom Meade, shares a profound...

2022 - 2025 $100,000 Glomerulonephritis, Kidney Biology A novel mouse model of MCD driven by podocyte autoantigen and T/B crosstalk Lay Abstract Kidneys act as a barrier that filters water and waste products into urine while retaining important proteins in blood. When this filtration barrier is...

2024 - 2026 $120,000 Glomerulonephritis Role of the extrafollicular B cell response in the production of anti-podocyte antibodies in idiopathic nephrotic syndrome Lay Abstract Background: Kidneys act as a barrier that filters water and waste products into urine while retaining important proteins in...

2022 - 2024 $100,000 Transplantation Effects of prednisone avoidance or tapering on mycophenolate exposure in adult kidney transplant patients Lay Abstract Kidney transplant recipients need to take multiple anti-rejection medications to ensure their body does not reject the transplanted organ....

2025 - 2027 $120,000 Transplantation Model-informed precision dosing of mycophenolic acid in pediatric kidney transplant recipients Co-Applicant(s):  Chia Wei Teoh, Lorraine Hamiwka, Lusine Tonoyan, Michelle Ruhl, Tom Blydt-Hansen Lay Abstract BACKGROUND: The drug mycophenolic acid (MPA) is...