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CENTRAL-CKD

General Audience Summary Purpose: In patients with the most severe form of chronic kidney disease, blood pressure (BP) control can be difficult as the margin of error between a too low BP and a too high BP is quite thin. Keeping the BP in the appropriate range helps minimis...

Our Volunteers

The Kidney Foundation of Canada research program appreciates the dedication and support of the research community.   A large number of community members contribute each year by actin as peer reviewers, reviewing and selecting the best research projects for funding through ...

Removal of mitochondrial health to improve the outcome of acute kidney injury

Acute kidney injury is the most common renal disease with no effective treatment. Acute kidney injury affects 3-7% of hospitalized patients with a patient mortality rate that exceeds that of breast and prostate cancers, heart failure and diabetes combined. After adverse kidney...

Describing Gut Microbiota in People with Chronic Kidney Disease

Lay Abstract A Deep Dive Into Understanding Gut Bacteria in Kidney Disease Background: People with kidney disease have more inflammation compared to the general population. This inflammation can show up in many ways, such as making gut health worse by damaging the good bact...

KIdney aNd blooD prESsure ouTcomes in Childhood Cancer Survivors (KINDEST CCS)

Supervisor(s): Michael Zappitelli Lay Summary Background : Due to better cancer research and treatments, more children with cancer are surviving, and for longer. However, childhood cancer survivors (CCS) are at high risk for many complications later in life. During cance...

Can Treatment with Lipid-lowering Medications Attenuate the Risk of Heart Attack and Stroke in patie

Supervisor(s): Aminu Bello Lay summary Background: Heart disease and strokes are major concerns for people undergoing dialysis, a treatment for severe kidney failure. Patients on dialysis have a significantly higher risk of serious medical conditions, such as heart att...

The impact of in utero arsenic exposure on kidney development and disease

Co-Applicant(s):  Aimee Ryan, Jenna Haverfield, Koren Mann Lay Abstract Background: Arsenic is a toxic substance found in nature and it’s dangerous to our health. We can come into contact with arsenic through the air we breathe, the water we drink, or the food we eat. T...

Evaluating Cardiovascular Therapies in Patients Living with Kidney Disease

Lay Abstract Background: People living with kidney disease are also at high risk for developing cardiovascular disease. Glucagon-like peptide-1 receptor agonists (GLP1RA) such as semaglutide are medications that help lower blood sugar, cause weight loss and have been shown...

Multi-omics in childhood nephrotic syndrome: toward targeted therapies

Lay Abstract Background: Nephrotic syndrome is the most common kidney disease in children worldwide. Rates of childhood nephrotic syndrome have doubled in the last 10 years in Canada, making it an important public health issue. Nephrotic syndrome is caused by injury to the...

Body Image and Self-Esteem: Men's Health

Body Image & Self Esteem Part 2: Men’s Health will share perspectives from men with kidney disease. Our patient partners will discuss issues like stretch marks, hair and weight changes, dialysis access and dating with CKD (chronic kidney disease). This webinar will empower yo...

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