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The epidemiology of urinary tract stone management in autosomal dominant polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder with no cure. Urinary tract stones are five to ten times more common in patients with ADPKD compared to the general population and increase morbidity by causing pain and accelerating disease progression...

Patient Forum 2024: Living Your Best Life with Kidney Disease

Join us this March 6 and 7, 2024 for our fourth virtual educational forum: Living Your Best Life with Kidney Disease. Developed in collaboration with people affected by kidney disease, their care partners, healthcare professionals, and researchers across Canada, this forum o...

The efficacy, mechanisms and safety of SGLT2i and GLP1RA combination therapy in kidney transplant re

Lay Abstract Kidney transplant recipients (KTR) are at high risk of death from heart disease after transplantation, as well as graft failure, where the kidney transplant no longer works and dialysis or another kidney transplant is required.  New types of drugs called sodium...

Be an Organ Donor

For many people living with kidney disease, a transplant offers the best chance at a healthier life. Organ donation saves lives and restores health. A kidney transplant is not a cure, but it offers the best possible improvement to health and quality of life for many people li...

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Person-centred perioperative risk prediction for people with kidney failure

Lay Abstract People with kidney failure have up to 16 times more surgeries than people without kidney disease. They also have worse outcomes after surgery including a higher risk of heart attacks and death. Canadian healthcare guidelines recommend that healthcare providers ...

Mechanism of tuberous sclerosis complex (TSC) kidney disease pathogenesis

Supervisor(s):   William Stanford Lay Abstract Background : Chronic kidney disease affects up to 13% of the population globally yet curative treatments are unavailable. Genetic contributors to chronic kidney disease are being increasingly recognized. Tuberous sclerosis c...

Preventing Kidney Disease by Preventing Protein Misfolding

Lay Summary Acute kidney injury (AKI) is sudden damage to the kidneys that causes them to not work properly. It occurs in one in five and one in three hospitalized adults and children, respectively. If the kidneys shut down completely, this may require temporary support in...

Risk of acute kidney injury in patients randomized to a restrictive versus liberal approach to red-b

Lay Summary When people have heart surgery their kidneys can sometimes be injured. This is known as “acute kidney injury”. This condition is very serious and sometimes causes kidney failure or death. To diagnose acute kidney injury, blood tests are needed before and after ...

Determining the influence of processes, structure and inter-professional relational networks within

Lay Summary Background: To optimize organ donation and transplantation the nature and impact of complex organizational characteristics, such as inter-professional roles and relationships, and hospital organizational structure processes, need to be understood. We know that ...

p-Cresol and mycophenolate interaction in adult kidney transplant patients

General Audience Summary Summary: Mycophenolate (or mycophenolic acid) is a commonly used medication for life-long maintenance to prevent the body from rejecting the transplanted kidney. Mycophenolate is usually prescribed in a fixed regimen, and almost all patients would ...

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