Skip to main content
Français National
Donate Now
Understanding the pathophysiology of uremic symptoms: a pilot mechanistic study of dialysate cooling

An alarming 24,000 Canadians (and over two million people worldwide) suffer from serious kidney failure and rely on a dialysis machine to clean their blood. Dialysis poses significant challenges; one in three patients die within a year of starting dialysis and those who underg...

Long-term kidney and heart outcomes after acute kidney injury among newborns and children

Lay Summary Acute kidney injury (AKI) is sudden damage to the kidneys that causes them to not work properly. It occurs in one in five and one in three hospitalized adults and children, respectively. If the kidneys shut down completely, this may require temporary support in...

Effect of an exercise rehabilitation program on symptom burden in hemodialysis: a randomized control

Lay Summary People with kidney failure who require hemodialysis to sustain life have multiple symptoms, such as fatigue, pain, and difficulty sleeping which are difficult to treat. This affects their ability to perform everyday activities, enjoy life, and likely increases ...

Modelling Alport syndrome using iPSC-derived glomeruli

Lay Summary One of the main roles of the kidney is to filter the blood, removing waste products and toxins. The units responsible for this filtration are called glomeruli, inside which two specialized cell types, the podocytes and the endothelial cells, create a barrier se...

Patient centered outcomes in childhood onset nephrotic syndrome

Lay Summary Nephrotic syndrome is the most common childhood kidney disease in the world. The rates of nephrotic syndrome have doubled over the past ten years in Ontario, where 5 children per 100,000 children are affected. South Asian children are affected by nephrotic synd...

Primary care physician involvement and quality of care for patients on dialysis

Lay Summary Background: Patients on dialysis have high healthcare needs that go beyond their regular dialysis treatments. Therefore, their care also includes preventative health, symptom management, mental health, and acute illness. Given patients’ frequent presence in the...

Fluid removal strategies on renal replacement therapy

Lay Summary Individuals who becomes critically ill and are admitted to the intensive care unit often develop kidney injury which can be severe enough to impair the ability to produce urine. In this setting, fluid is likely to accumulate and this may cause important complica...

Potential roles of antibodies in the pathogenesis of nephrotic syndrome

Lay Summary Nephrotic syndrome (NS) is a common form of kidney disease that happens when the kidney leaks a massive quantity of protein in the urine. This continuous loss of protein creates body swelling and is toxic to the kidney. Untreated, it leads to chronic kidney dise...

The Impact of Subclinical Primary Aldosteronism on Kidney Disease

General Audience Summary Background: Hypertension (high blood pressure) management generally involves a ‘one size fits all’ approach. Employing a more personalized approach targeting the specific cause of an individual patient’s hypertension provides the opportunity to impr...

Examining the Impact of the COVID-19 Pandemic on Chronic Kidney Disease Patients, their Family Careg

Lay Abstract The COVID-19 pandemic has been a very difficult process and experience for so many. It has been especially tough for people with kidney disease, their families and support systems, and for health care providers. Unfortunately, we don’t know too much about how t...

|<  <   1 2 3 4 5 6 7 8 9 10 ...   >  >| Pages: 3 of 14